Motif ID: FOX{F1,F2,J1}.p2

Z-value: 1.134


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXJ1chr17_-_741373700.393.6e-09Click!
FOXF1chr16_+_865441040.194.8e-03Click!
FOXF2chr6_+_1390068-0.028.2e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_88450243 26.327 SPARCL1
SPARC-like 1 (hevin)
chr5_-_42811959 19.099 NM_001085486
NM_001093726
NM_005410
 SEPP1


selenoprotein P, plasma, 1


chr1_-_161193375 18.582 NM_001643
 APOA2
apolipoprotein A-II
chr14_-_74551159 17.987 NM_005589
 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr17_-_29641068 17.053 EVI2B
ecotropic viral integration site 2B
chr14_-_74551073 17.042 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_-_161193190 16.802 APOA2
apolipoprotein A-II
chr14_-_21493122 16.505 NM_201538
NM_201539
NM_201540
NM_201541
 NDRG2



NDRG family member 2



chr11_+_1151578 13.896 MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr11_+_113931228 13.648 NM_001018011
 ZBTB16
zinc finger and BTB domain containing 16
chr17_-_29641087 13.644 EVI2B
ecotropic viral integration site 2B
chr4_+_74269971 13.600 NM_000477
 ALB
albumin
chr1_+_207277577 13.078 NM_000715
 C4BPA
complement component 4 binding protein, alpha
chr17_-_29641094 12.784 NM_006495
 EVI2B
ecotropic viral integration site 2B
chr4_-_176734181 12.435 NM_201591
 GPM6A
glycoprotein M6A
chr4_+_74270832 11.607 ALB
albumin
chr4_-_72671236 10.899 NM_001204306
 GC
group-specific component (vitamin D binding protein)
chr1_+_227127993 10.670 ADCK3
aarF domain containing kinase 3
chr19_-_36523770 10.515 NM_015526
 CLIP3
CAP-GLY domain containing linker protein 3
chr17_-_26697293 10.491 VTN
vitronectin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 43 entries
enrichment   p-value GO term description
8.46 1.75e-02 GO:0015721 bile acid and bile salt transport
6.27 4.58e-04 GO:0008206 bile acid metabolic process
4.76 8.22e-04 GO:0010951 negative regulation of endopeptidase activity
4.73 7.11e-07 GO:0007586 digestion
4.22 4.58e-02 GO:0016064 immunoglobulin mediated immune response
4.12 2.72e-02 GO:0072376 protein activation cascade
3.05 1.94e-02 GO:0051346 negative regulation of hydrolase activity
3.00 2.15e-05 GO:0008202 steroid metabolic process
2.86 3.16e-02 GO:0002252 immune effector process
2.80 4.38e-02 GO:0019935 cyclic-nucleotide-mediated signaling
2.63 4.37e-03 GO:0002253 activation of immune response
2.52 7.52e-04 GO:0019932 second-messenger-mediated signaling
2.50 1.39e-03 GO:0050778 positive regulation of immune response
2.40 1.60e-05 GO:0050776 regulation of immune response
2.37 8.43e-07 GO:0007186 G-protein coupled receptor protein signaling pathway
2.00 4.94e-03 GO:0051336 regulation of hydrolase activity
1.98 1.91e-02 GO:0007596 blood coagulation
1.98 1.91e-02 GO:0050817 coagulation
1.97 2.27e-02 GO:0007599 hemostasis
1.91 1.72e-02 GO:0050878 regulation of body fluid levels

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
4.12 3.76e-02 GO:0031093 platelet alpha granule lumen
4.09 1.83e-02 GO:0031983 vesicle lumen
4.03 4.53e-02 GO:0034774 secretory granule lumen
3.73 4.41e-02 GO:0031091 platelet alpha granule
2.05 2.78e-07 GO:0005615 extracellular space
1.96 3.00e-08 GO:0044421 extracellular region part
1.89 9.33e-09 GO:0005887 integral to plasma membrane
1.87 1.41e-08 GO:0031226 intrinsic to plasma membrane
1.64 4.53e-09 GO:0044459 plasma membrane part
1.64 1.46e-02 GO:0005626 insoluble fraction
1.62 1.59e-03 GO:0000267 cell fraction
1.55 4.81e-06 GO:0005576 extracellular region
1.41 1.59e-08 GO:0005886 plasma membrane
1.41 1.81e-08 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
3.34 2.05e-02 GO:0004867 serine-type endopeptidase inhibitor activity
3.19 1.15e-02 GO:0016298 lipase activity
1.54 1.13e-02 GO:0004888 transmembrane receptor activity
1.45 1.40e-02 GO:0004872 receptor activity
1.41 6.93e-03 GO:0004871 signal transducer activity
1.41 6.93e-03 GO:0060089 molecular transducer activity