Motif ID: FOX{F1,F2,J1}.p2

Z-value: 1.134


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXJ1chr17_-_741373700.393.6e-09Click!
FOXF1chr16_+_865441040.194.8e-03Click!
FOXF2chr6_+_1390068-0.028.2e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_88450243 26.327 SPARCL1
SPARC-like 1 (hevin)
chr5_-_42811959 19.099 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr1_-_161193375 18.582 NM_001643
APOA2
apolipoprotein A-II
chr14_-_74551159 17.987 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr17_-_29641068 17.053 EVI2B
ecotropic viral integration site 2B
chr14_-_74551073 17.042 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_-_161193190 16.802 APOA2
apolipoprotein A-II
chr14_-_21493122 16.505 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr11_+_1151578 13.896 MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr11_+_113931228 13.648 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr17_-_29641087 13.644 EVI2B
ecotropic viral integration site 2B
chr4_+_74269971 13.600 NM_000477
ALB
albumin
chr1_+_207277577 13.078 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr17_-_29641094 12.784 NM_006495
EVI2B
ecotropic viral integration site 2B
chr4_-_176734181 12.435 NM_201591
GPM6A
glycoprotein M6A
chr4_+_74270832 11.607 ALB
albumin
chr4_-_72671236 10.899 NM_001204306
GC
group-specific component (vitamin D binding protein)
chr1_+_227127993 10.670 ADCK3
aarF domain containing kinase 3
chr19_-_36523770 10.515 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr17_-_26697293 10.491 VTN
vitronectin
chr14_+_74551655 10.241 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr1_+_227127959 10.150 ADCK3
aarF domain containing kinase 3
chr17_-_26697310 10.147 VTN
vitronectin
chr17_-_26697224 10.134 VTN
vitronectin
chr12_-_96390002 10.051 NM_002108
HAL
histidine ammonia-lyase
chr18_-_53068755 9.967 TCF4
transcription factor 4
chr7_-_140624280 9.686 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr12_+_79258588 9.637 SYT1
synaptotagmin I
chr1_+_227127999 9.212 ADCK3
aarF domain containing kinase 3
chr5_-_131132642 9.146 FNIP1
folliculin interacting protein 1
chr16_+_56225301 8.990 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr17_-_7082559 8.853 ASGR1
asialoglycoprotein receptor 1
chr4_+_71587674 8.853 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr10_+_5005601 8.837 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr11_-_114466397 8.679 FAM55D
family with sequence similarity 55, member D
chr14_+_100563817 8.579 EVL
Enah/Vasp-like
chr6_+_44244465 8.359 TMEM151B
transmembrane protein 151B
chr11_-_5526833 8.255 NM_001005567
OR51B5
HBE1
olfactory receptor, family 51, subfamily B, member 5
hemoglobin, epsilon 1
chr9_-_116840545 8.187 AMBP
alpha-1-microglobulin/bikunin precursor
chr22_+_21128378 8.157 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr13_-_46756326 8.053 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr10_+_5005453 8.002 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr4_-_72669757 8.002 NM_001204307
GC
group-specific component (vitamin D binding protein)
chr1_-_57431620 7.933 NM_000066
C8B
complement component 8, beta polypeptide
chr2_+_33661392 7.846 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr10_-_52645384 7.840 A1CF
APOBEC1 complementation factor
chr14_+_95078713 7.695 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr15_-_40599872 7.225 PLCB2
phospholipase C, beta 2
chr13_-_41240607 7.214 NM_002015
FOXO1
forkhead box O1
chr19_-_36523540 7.169 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr9_-_116840460 7.130 AMBP
alpha-1-microglobulin/bikunin precursor
chr15_-_40600118 6.955 NM_004573
PLCB2
phospholipase C, beta 2
chr4_-_87028805 6.914 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr13_-_46756295 6.758 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr5_+_176853673 6.736 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr22_-_36019363 6.735 NM_203377
MB
myoglobin
chr9_-_116840551 6.676 AMBP
alpha-1-microglobulin/bikunin precursor
chr10_+_70847817 6.605 NM_002727
SRGN
serglycin
chr4_+_88754120 6.465 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr15_-_40600025 6.386 PLCB2
phospholipase C, beta 2
chr10_+_70847857 6.359 SRGN
serglycin
chr14_-_21493910 6.359 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr14_-_21493858 6.341 NDRG2
NDRG family member 2
chr1_+_150122415 6.295 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr12_-_49504337 6.281 LMBR1L
limb region 1 homolog (mouse)-like
chr8_+_1952875 6.275 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr19_+_50380681 6.264 NM_001168222
NM_024682
TBC1D17

TBC1 domain family, member 17

chr2_+_89185055 6.222


chr4_+_88720701 6.194 NM_004967
IBSP
integrin-binding sialoprotein
chrX_+_70315637 6.024 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr9_-_77503009 5.968 NM_017662
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr7_+_134832765 5.864 NM_018295
TMEM140
transmembrane protein 140
chr7_+_5229911 5.848 WIPI2
WD repeat domain, phosphoinositide interacting 2
chr10_+_5005685 5.837 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr5_-_59064437 5.813 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_155484131 5.770 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr8_+_79428335 5.763 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr11_-_114466471 5.748 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr9_-_135819995 5.725 NM_000368
NM_001162426
NM_001162427
TSC1


tuberous sclerosis 1


chr16_+_77233348 5.651 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr19_+_50031232 5.569 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr12_-_11548485 5.566 NM_006248
PRB1
PRB2
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 2
chr11_-_116708334 5.524 NM_000039
APOA1
apolipoprotein A-I
chr2_+_220042948 5.510 FAM134A
family with sequence similarity 134, member A
chr7_-_87342569 5.501 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr4_-_155511838 5.500 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chrX_+_57618440 5.493 ZXDB
zinc finger, X-linked, duplicated B
chr17_+_58755158 5.490 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr3_+_50712671 5.455 NM_004947
DOCK3
dedicator of cytokinesis 3
chr17_-_7082654 5.443 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr7_+_106505739 5.401 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr17_+_72427535 5.385 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr10_-_5045967 5.335 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr14_-_101036130 5.326 NM_020836
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr4_+_68424444 5.314 NM_012108
STAP1
signal transducing adaptor family member 1
chr4_-_39033981 5.302 NM_024943
TMEM156
transmembrane protein 156
chr22_+_23054862 5.300 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr5_+_54398473 5.283 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr14_-_94789641 5.271 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr1_+_198608244 5.238 PTPRC
protein tyrosine phosphatase, receptor type, C
chr3_+_189349215 5.141 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr12_-_10251520 5.138 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr17_+_48172100 5.087 NM_001199898
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr5_-_169724614 5.058 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_+_23987514 5.051 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr6_-_41715078 5.041 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr12_+_79439432 4.998 NM_001135806
SYT1
synaptotagmin I
chr12_-_11508509 4.959 NM_005039
NM_199353
NM_199354
PRB1


proline-rich protein BstNI subfamily 1


chr8_+_23427477 4.931 SLC25A37
solute carrier family 25, member 37
chr1_-_230850335 4.926 NM_000029
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr7_+_129906702 4.925 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr12_-_52779362 4.910 NM_033045
KRT84
keratin 84
chr15_+_74907334 4.894 NM_001130028
CLK3
CDC-like kinase 3
chr20_+_31823801 4.840 NM_001243193
NM_016583
NM_130852
BPIFA1


BPI fold containing family A, member 1


chr7_+_44646180 4.836 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr3_-_39321479 4.831 NM_001337
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr17_-_2996289 4.812 NM_002548
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr3_-_10547340 4.804 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chrX_-_48693934 4.722 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_+_169929009 4.692 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr5_+_36606667 4.684 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr13_-_99910548 4.681 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr8_-_110655418 4.668 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr7_+_5229886 4.666 WIPI2
WD repeat domain, phosphoinositide interacting 2
chr17_-_3195875 4.665 NM_002550
OR3A1
olfactory receptor, family 3, subfamily A, member 1
chr11_+_60260250 4.644 NM_001164470
NM_017716
MS4A12

membrane-spanning 4-domains, subfamily A, member 12

chr6_-_32784727 4.636 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr10_+_52751114 4.627 PRKG1
protein kinase, cGMP-dependent, type I
chr6_+_108882104 4.623 FOXO3
forkhead box O3
chr16_-_86542463 4.603 LOC400550
uncharacterized LOC400550
chr19_-_58609574 4.548 ZSCAN18
zinc finger and SCAN domain containing 18
chr2_-_71454200 4.511 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr7_+_5229920 4.448 WIPI2
WD repeat domain, phosphoinositide interacting 2
chr20_-_44993000 4.447 NM_015945
NM_173073
NM_173179
SLC35C2


solute carrier family 35, member C2


chr1_+_227127937 4.423 NM_020247
ADCK3
aarF domain containing kinase 3
chrX_+_100333835 4.399 NM_021637
TMEM35
transmembrane protein 35
chr19_-_36236291 4.378 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr9_-_134585107 4.346 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr19_-_52255099 4.335 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr7_-_143059144 4.335 NM_014690
FAM131B
family with sequence similarity 131, member B
chr12_-_99038401 4.328 NM_153687
NM_201612
NM_201613
IKBIP


IKBKB interacting protein


chr16_+_81812897 4.316 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_+_220701800 4.314 MARK1
MAP/microtubule affinity-regulating kinase 1
chr4_+_100495972 4.300 MTTP
microsomal triglyceride transfer protein
chr1_+_241695433 4.281 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr6_+_31895201 4.269 NM_000063
NM_001145903
C2

complement component 2

chr13_-_36920396 4.243 SPG20
spastic paraplegia 20 (Troyer syndrome)
chr14_-_70263871 4.233 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr16_+_30483959 4.232 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr14_-_106733392 4.217 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr1_+_220960038 4.188 NM_022746
MARC1
mitochondrial amidoxime reducing component 1
chr12_-_9268522 4.187 NM_000014
A2M
alpha-2-macroglobulin
chr20_-_52687014 4.130 BCAS1
breast carcinoma amplified sequence 1
chr6_+_72922513 4.122 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chrX_-_65259839 4.073 NM_001100431
NM_001184830
NM_001184831
NM_007268
VSIG4



V-set and immunoglobulin domain containing 4



chr20_-_44563684 4.060 FLJ40606
uncharacterized LOC643549
chr1_+_198608216 4.048 PTPRC
protein tyrosine phosphatase, receptor type, C
chr19_-_52531517 4.040 NM_025040
ZNF614
zinc finger protein 614
chr18_+_21033263 4.037 RIOK3
RIO kinase 3 (yeast)
chr16_+_81812899 4.023 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr13_-_46756291 4.022 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_-_34313685 4.005 NM_032962
NM_032963
CCL14

chemokine (C-C motif) ligand 14

chr16_-_1832576 4.001 NM_080861
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr4_+_72102249 3.986 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr4_-_87374282 3.979 NM_002753
MAPK10
mitogen-activated protein kinase 10
chr19_+_1207129 3.976 EFNA2
ephrin-A2
chr1_+_43855549 3.952 NM_015284
SZT2
seizure threshold 2 homolog (mouse)
chr9_-_116840604 3.931 AMBP
alpha-1-microglobulin/bikunin precursor
chr2_-_219031646 3.929 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chrX_+_46940235 3.913 RGN
regucalcin (senescence marker protein-30)
chr10_+_51549552 3.912 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr5_-_58571916 3.907 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr16_+_81812925 3.833 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_+_43855599 3.833 SZT2
seizure threshold 2 homolog (mouse)
chr12_+_101988746 3.830 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr4_-_153273683 3.752 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr17_-_26697358 3.745 NM_000638
VTN
vitronectin
chr10_+_7745341 3.708 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr8_-_134309448 3.696 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr4_-_100212085 3.685 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr6_-_32977312 3.683 HLA-DOA
major histocompatibility complex, class II, DO alpha
chr9_+_120466453 3.683 NM_138554
TLR4
toll-like receptor 4
chr6_+_101846860 3.673 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr19_-_51531283 3.663 NM_001167605
NM_006853
KLK11

kallikrein-related peptidase 11

chr2_+_162272619 3.654 NM_006593
TBR1
T-box, brain, 1
chr1_+_160765927 3.653 NM_001033667
NM_002348
LY9

lymphocyte antigen 9

chr19_-_46148606 3.630 NM_001193268
EML2
echinoderm microtubule associated protein like 2
chr7_-_25268057 3.618 NM_022150
NPVF
neuropeptide VF precursor
chr1_-_186649421 3.558 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_87755880 3.554 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr21_+_39644428 3.548 NM_170737
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr7_+_106505876 3.546 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_+_150122246 3.541 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr10_-_52645430 3.528 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr13_-_49975734 3.509 NM_030925
CAB39L
calcium binding protein 39-like
chr1_+_150122095 3.502 NM_016274
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr11_-_9225780 3.501 DENND5A
DENN/MADD domain containing 5A
chr13_-_36788665 3.494 NM_017826
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr12_+_69201979 3.493 MDM2
Mdm2 p53 binding protein homolog (mouse)
chr2_-_175260349 3.471 NM_004882
CIR1
corepressor interacting with RBPJ, 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.76 1.10e-08 GO:0007166 cell surface receptor linked signaling pathway
1.46 4.10e-08 GO:0023052 signaling
1.30 6.25e-07 GO:0050896 response to stimulus
4.73 7.11e-07 GO:0007586 digestion
2.37 8.43e-07 GO:0007186 G-protein coupled receptor protein signaling pathway
1.44 3.15e-06 GO:0007165 signal transduction
1.63 5.13e-06 GO:0048583 regulation of response to stimulus
1.32 1.14e-05 GO:0032501 multicellular organismal process
1.22 1.56e-05 GO:0065007 biological regulation
2.40 1.60e-05 GO:0050776 regulation of immune response
3.00 2.15e-05 GO:0008202 steroid metabolic process
1.90 5.16e-05 GO:0009611 response to wounding
1.35 1.20e-04 GO:0051716 cellular response to stimulus
1.50 4.31e-04 GO:0065008 regulation of biological quality
6.27 4.58e-04 GO:0008206 bile acid metabolic process
1.62 6.32e-04 GO:0065009 regulation of molecular function
2.52 7.52e-04 GO:0019932 second-messenger-mediated signaling
1.21 7.67e-04 GO:0050789 regulation of biological process
4.76 8.22e-04 GO:0010951 negative regulation of endopeptidase activity
2.50 1.39e-03 GO:0050778 positive regulation of immune response
1.75 2.19e-03 GO:0006629 lipid metabolic process
1.54 4.24e-03 GO:0023051 regulation of signaling
2.63 4.37e-03 GO:0002253 activation of immune response
2.00 4.94e-03 GO:0051336 regulation of hydrolase activity
1.78 6.60e-03 GO:0006952 defense response
1.41 1.07e-02 GO:0006950 response to stress
1.62 1.08e-02 GO:0050790 regulation of catalytic activity
1.60 1.20e-02 GO:0002376 immune system process
1.79 1.30e-02 GO:0006955 immune response
1.91 1.72e-02 GO:0050878 regulation of body fluid levels
8.46 1.75e-02 GO:0015721 bile acid and bile salt transport
1.81 1.88e-02 GO:0002682 regulation of immune system process
1.98 1.91e-02 GO:0007596 blood coagulation
1.98 1.91e-02 GO:0050817 coagulation
3.05 1.94e-02 GO:0051346 negative regulation of hydrolase activity
1.19 2.15e-02 GO:0050794 regulation of cellular process
1.41 2.23e-02 GO:0042221 response to chemical stimulus
1.97 2.27e-02 GO:0007599 hemostasis
4.12 2.72e-02 GO:0072376 protein activation cascade
2.86 3.16e-02 GO:0002252 immune effector process
1.52 3.45e-02 GO:0009966 regulation of signal transduction
2.80 4.38e-02 GO:0019935 cyclic-nucleotide-mediated signaling
4.22 4.58e-02 GO:0016064 immunoglobulin mediated immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.64 4.53e-09 GO:0044459 plasma membrane part
1.89 9.33e-09 GO:0005887 integral to plasma membrane
1.87 1.41e-08 GO:0031226 intrinsic to plasma membrane
1.41 1.59e-08 GO:0005886 plasma membrane
1.41 1.81e-08 GO:0071944 cell periphery
1.96 3.00e-08 GO:0044421 extracellular region part
2.05 2.78e-07 GO:0005615 extracellular space
1.55 4.81e-06 GO:0005576 extracellular region
1.62 1.59e-03 GO:0000267 cell fraction
1.64 1.46e-02 GO:0005626 insoluble fraction
4.09 1.83e-02 GO:0031983 vesicle lumen
4.12 3.76e-02 GO:0031093 platelet alpha granule lumen
3.73 4.41e-02 GO:0031091 platelet alpha granule
4.03 4.53e-02 GO:0034774 secretory granule lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.41 6.93e-03 GO:0004871 signal transducer activity
1.41 6.93e-03 GO:0060089 molecular transducer activity
1.54 1.13e-02 GO:0004888 transmembrane receptor activity
3.19 1.15e-02 GO:0016298 lipase activity
1.45 1.40e-02 GO:0004872 receptor activity
3.34 2.05e-02 GO:0004867 serine-type endopeptidase inhibitor activity